A*Midex (Aix-Marseille Initiative of Excellence)
PhD in biophysics : Mechanotransmission, mechanotransduction, lamina and cellular senescence
A*Midex (Aix-Marseille Initiative of Excellence)
The Foundation will run the funding allocated to the A*MIDEX project, i.e. close to 26 million euros a year.
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OM TJÄNSTEN
Publicerad: 1 månad sedan
Sista ansökningsdatum: jun 30
Plats: Marseille Cedex 07, Frankrike
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DELA DETTA JOBB

PhD in biophysics : Mechanotransmission, mechanotransduction, lamina and cellular senescence

General informations

Length : 36 months
Starting date :   Oct, 1st 2018
Working time : Full time
Salary : 1 768.55 euros/month (gross salary)
Diploma : Master

Task

The project aims at correlating genetic mutations in laminopathies with defects in nuclear enveloppe resulting in premature aging of cells. The phD student will develop microfluidic experiments compatible with optical microscopy to quantify cell and nucleus mechanical properties as function of the mutation level.

Activities

  • Interaction with physicists and biologists
  • Cell culture, cell treatments with biochemicals, cell handling
  • Design and fabrication of microfluidic devices
  • Microscopy observation and video acquisition, image analysis
  • Presentation of results in lab meetings and conferences

Expertise

  • Knowledge
    • English : B2 to C1
    • Physics of soft matter
    • Basics in biology and optical microscopy
    • Basics in programming : Matlab or Python
  •  
  • Operating expertise
    • Optical microscopy
    • Imaging software: ImageJ
    • Programming to extract data from image analysis and compile results

Working environment

  •  
  • Working place : the PhD student is affiliated to Aix Marseille Université but her/his working place if the  Interdisciplinary Nanoscience Centre in Marseille (CINaM, AMU/CNRS UMR 7325)
  • Special conditions : -

To apply

Please send CV, motivation letter and recommandations letters from previous advisors to helfer@cinam.univ-mrs.fr before June, 30th 2018

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