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Princess Margaret Cancer Centre
Bioinformatics Postdoctoral Fellow and Bioinformatics Research Associate
Princess Margaret Cancer Centre
Princess Margaret is one of the largest cancer centres in the world.
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Publicerad: 9 månader sedan
Sista ansökningsdatum: Ospecificerad
Plats: Toronto, Kanada
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Bioinformatics Postdoctoral Fellow and Bioinformatics Research Associate

Two funded positions are available in the De Carvalho Lab at Princess Margaret Cancer Centre/University of Toronto: Bioinformatics Postdoctoral Fellow and Bioinformatics Research Associate.

The focus of the projects are in translational cancer epigenomics, with multiple projects available in Methylome profiling of cancer cells and circulating cell-free DNA (‘liquid biopsy’) for cancer classification, early detection and disease monitoring; Cancer Epigenetics therapy to target cancer stem cells and to increase anti-tumour immune response. The projects will include epigenomic approaches such as ChIP-seq, ATAC-seq, CUT&RUN, RRBS, WGBS among others and functional approaches such as CRISPR screening.

The research will be conducted at the princess Margaret Cancer Centre, a research hospital affiliated to the University of Toronto, in one of the most liveable city in the world.

The ideal candidate should have:

  • PhD in computational biology, bioinformatics, biostatistics, cancer biology, epigenomics, genomics, or a related field;
  • Experience with epigenomics and transcriptomics data analysis from ChIP-seq, ATAC-seq, RRBS, WGBS, RNA-seq experiments;
  • Experience with large data-sets (e.g., ENCODE, TCGA, GTEx);
  • Experience with Machine Learning/Deep Learning applied to biology or oncology;
  • Proficiency in general-purpose programming language and scientific data processing ecosystem (e.g. R, R-studio);
  • Good publication record.

Those interested in the position described should submit full CV and cover letter to Dr. Daniel D. De Carvalho (epigenome.search@gmail.com)

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