Diary id: PAR 2020/975
Employment level: Fixed term
Location: Department of Chemistry and Molecular Biology
Apply by: 2020-10-16
Research and graduate education at the department of chemistry and molecular biology comprises a wide scientific field from the atomic and molecular levels all the way through cells to intact organisms. Much of the phenomena studied here impact on our natural environment and living systems. We participate in undergraduate programs in chemistry, molecular biology, medicinal chemistry, biology, marine sciences, and pharmacy.
Rapid progress in life sciences is mostly methodology driven. Nuclear Magnetic Resonance (NMR) is an actively developing biophysical technique that provides atomic-level information about spatial structure, dynamics, and interactions of key molecular components of a living cell. Our group at the Department of Chemistry and Molecular Biology and the Swedish NMR Centre is the forefront of developing new NMR experiments, signal processing algorithms, automation of data analysis. The new methodology is immediately applied and tested in our studies of structure and dynamics of Intrinsically Disordered Proteins and large proteins systems (look for Vladislav Orekhov’s profile on google scholars).
The Department of Chemistry and Molecular Biology and Swedish NMR Centre offers an international and enthusiastic working environment with excellent infrastructure for studies in all areas of life science. Our facilities for structural biology include state-of-the-art 600-900 MHz Bruker NMR spectrometers, access to national super-computer infrastructure, as well as a fully equipped biochemistry laboratory for expression, purification, and biophysical characterization. Our group is involved in a broad network of research collaboration in Sweden and worldwide.
The PhD student will be involved in developing of an efficient NMR-centered Structural Biology platform for tackling deficiencies of the present-day NMR spectroscopy. These are insufficient resolution, sensitivity, and efficiency of analysis when dealing with real-life proteins systems and molecular complexes such as large and intrinsically disordered proteins.
The new methodology will deviate from the traditional approach of uniform data sampling and universal broadband experiments. In contrast, we will develop a task-oriented technique that combines a novel set of spin system optimized selective NMR experiments with fast targeted data acquisition, next-generation digital signal processing by compressed sensing and artificial intelligence.
Based on our experience, novel ideas, and broad network of local and international collaborations, the platform will be developed, tested, and fine-tuned in studies several several biomedically important systems.
The PhD student will be exposed to a broad range of scientific tasks and research questions that require a genuine interest to acquire knowledge in NMR, Structural Biology, Biophysics, Signal Processing, Artificial Intelligence, Molecular modelling, as well as in novel methods of protein expression and purification.
To be eligible for third-cycle studies, the applicant must meet both the general and specific entry requirements: A person meets the general entry requirements for third-cycle courses and study programs if he or she:
To meet the specific entry requirements for third-cycle studies, applicants must: (i) have a second-cycle (advanced-level) degree in a relevant* subject area in the natural sciences, or (ii) have completed studies for at least 60 higher education credits at a second-cycle level in relevant subject areas in the natural sciences, or (iii) have completed a corresponding program of relevance to the planned third-cycle program, in Sweden or in another country, or have equivalent qualifications.
*Relevant for the planned third-cycle education
The specific entry requirements also include an acceptable level of spoken and written English. Guidelines for assessing English proficiency may include a minimum score of 550 on the TOEFL test (or 213 on the TOEFL-CBT, or 79 on the TOEFL-iBT).
In selecting between applicants who meet the general and specific entry requirements, their ability to benefit from third-cycle studies will be considered. The assessment shall attach particular importance to documented qualifications for: physics, math, and chemistry/biology. Knowledge in artificial intelligence, programming (e.g. python, MATLAB, or C), biophysical methods of protein characterization, and methods of protein expression and purification are also welcome.
We seek a talented and dedicated student eager to pursue a career in Structural Biology and Biophysics. You should be open-minded and have a genuine interest in Math, Physics, and Life-science. You should be able to work independently and in a team, as well as to communicate well in English.
Type of employment: Fixed-term employment, four years full time
Extent: 100 %
Location: Department of Chemistry and Molecular Biology, Gothenburg
First day of employment: As soon as possible based on agreement
Regulations for the evaluation of qualifications for education on a doctoral level are given in SFS 1993:100.
A new employment as a PhD student applies for a maximum of one year. The Appointment may be prolonged for up to two years at a time. The total employment period may not be longer than the equivalent of four years of full time doctoral studies.
University applies local agreement on salaries of graduate students.
Professor Vladislav Orekhov, firstname.lastname@example.org
Phone number: +46 31 786 3886
Union representatives at the University of Gothenburg: http://www.gu.se/english/about_the_university/job-opportunities/union-representatives
Choosing a career in a foreign country is a big step. Thus, to give you a general idea of what we and Gothenburg have to offer in terms of benefits and life in general for you and your family/spouse/partner please visit:
In order to apply for a position at the University of Gothenburg, you have to register an account in our online recruitment system. It is the responsibility of the applicant to ensure that the application is complete in accordance with the instructions in the job advertisement, and that it is submitted before the deadline.
You must include the following, in PDF format
If your degree is from a university outside of Sweden, check what you need to submit at https://www.universityadmissions.se/en/All-you-need-to-know1/Applying-for-studies/Documenting-your-eligibility-for-studies/Instructions-for-Masters-applicants/Specific-requirements-for-my-country1/where you can also see what you need to submit in order to fulfill the English language requirement.
If your degree has not been verified by a Swedish authority you need to provide contact details to the issuing university, registrar or similar, that can verify the degree at our request.
Closing date: 2020-10-16
The University of Gothenburg promotes equal opportunities, equality and diversity.
Applications will be destroyed or returned (upon request) two years after the decision of employment has become final. Applications from the employed and from those who appeal the decision will not be returned.Läs mer
|Titel||PhD position in Biophysics: Biomolecular NMR methodology|
|Job location||Vasagatan 33, 411 37 Göteborg|
|Publicerad||augusti 26, 2020|
|Sista ansökningsdatum||oktober 16, 2020|
|Ämnen||Biofysik,   Strukturbiologi,   Molekylärbiologi,   Spektroskopi  |