CBS - Postdoctoral Research Fellow in Microbiome Dysbiosis and Disease Mechanisms

Institution / Department

Mohammed VI Polytechnic University
Chemical & biochemical sciences.green process engineering
Research Unit on Microbiome and Host-Pathogen Interactions

Project Overview

We are seeking a talented and motivated Postdoctoral Research Fellow to join our dynamic team investigating the role of microbiome dysbiosis in human health and disease. The project focuses on deciphering how imbalances in the gut microbiota contribute to chronic inflammatory conditions, colorectal cancer (CRC), and immune dysfunction, with an emphasis on discovering biomarkers and developing microbiome-based therapies.

The research integrates multi-omics approaches (metagenomics, transcriptomics, proteomics, metabolomics) to understand how dysbiosis influences immune responses, barrier function, and host metabolism.

Key Responsibilities

• Lead metagenomic, proteomics, and metabolomic profiling of clinical and experimental samples to identify dysbiosis signatures.
• Apply bioinformatics tools for microbiome data analysis (ex, QIIME2, MetaPhlAn, Kraken2).
• Collaborate on multi-omics data integration and analysis.
• Contribute to manuscript writing, conference presentations, and grant applications.

Required Qualifications

• PhD in Microbiology, Immunology, Systems Biology, Bioinformatics, or a related discipline.
• Proven experience in microbiome research, particularly in gut microbiota.
• Experience with next-generation sequencing (NGS) and omics data analysis.
• Knowledge of microbial ecology, dysbiosis, and host-microbiome interactions.
• Familiarity with cell culture techniques.
• R, Python, or other data science tools for microbiome analysis.
• Publication record in peer-reviewed journals.

Preferred Qualifications

• Experience with colorectal cancer models or inflammatory bowel disease (IBD).
• Familiarity with metabolomics (LC-MS, GC-MS) and analysis of microbial metabolites.
• Expertise in interkingdom microbiome research (fungi, viruses, archaea).
• Understanding of immunomodulation by the microbiota in cancer and chronic inflammation.

Why Join Us?

• Work at the frontier of precision microbiome medicine and immune-oncology.
• Access to state-of-the-art facilities for genomics, proteomics, and metabolomics.
• Join an international, multidisciplinary team with collaborations across the US/Canada/Europe/Asia.
• Opportunity to lead high-impact publications and develop independent research projects.

Application Process:

Applicants should submit the following in a single PDF file:

1. A Cover Letter explaining their interest and fit for the position
2. A detailed Curriculum Vitae (CV)
3. Names and contact details of 2–3 references
4. Up to three key publications (optional)